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None of the 10 comatose patients had myoclonus status epilepticus or fixed, dilated pupils on neurologic examination, and none had abnormal somatosensory-evoked potentials. Eight patients showed diffuse signal abnormalities, predominantly in the cerebellum (n=5), the thalamus (n=8), the frontal and parietal cortices (n=8), and the hippocampus (n=9). One patient showed normal MR imaging results, and one patient had abnormalities in the thalamus and cerebellum and minimal abnormality on DW imag es; both later awakened. None of the patients with abnormal cortical structures on FLAIR MR images recovered beyond a severely disabled state. MR imaging in comatose survivors may parallel the pathologic findings in severe anoxic-ischemic injury, and ex tensive abnormalities may indicate little to no prospects for recovery. If confirmed, MR imaging may have a role as a prognosticating rest in anoxic-ischemic coma. |
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cardiac arrest
cardiac arrest and resuscitation
coma
coma,prognosis of
hippocampus
hypoxic encephalopathy
hypoxic-ischemic leukoencephalopathy
leukoencephalopathy
life support,withdrawal of
MRI
MRI,abnormal
MRI,diffusion weighted
MRI,FLAIR
prognosis
thalamus,lesion of-bilateral
white matter disease
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